Nicotinamide adenine dinucleotide (NAD+) is a coenzyme present in every living cell. It is essential for hundreds of metabolic processes, including the conversion of food into cellular energy, DNA repair, and regulation of circadian rhythms.
NAD+ levels decline significantly with age. By the time a person reaches 60, their NAD+ levels may be half of what they were at 20. This decline has been linked in research to age-related metabolic dysfunction, mitochondrial deterioration, and reduced cellular repair capacity.
Research into NAD+ supplementation has explored multiple delivery methods including oral precursors (NMN, NR) and direct intravenous or subcutaneous administration. Injectable NAD+ bypasses the digestive system, which may offer more direct bioavailability.
Preclinical studies have investigated NAD+ for its role in activating sirtuins, a family of proteins involved in aging and longevity. Sirtuins require NAD+ as a cofactor, and their activity appears to correlate with NAD+ availability.
NAD+ is supplied as a lyophilized powder for research use. Proper storage at low temperatures is critical as the molecule can degrade when exposed to heat or moisture.
Disclaimer: This article is for educational purposes only. All peptides are sold for laboratory research use only. Not for human consumption.